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This may be due to the vicious cycle of increased lipid peroxidation and free radicals in cancer cells, while the decrease in GPx activity makes cancer tissues more susceptible to the damaging effects of free radicals

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LPO products can abrogate the function of PI3K specifically by caused conformational change that leads to the removal of the catalytic subunit or by competition with the regulatory subunit [111,112,113]

doi: 10.3389/fimmu.2025.1537405 Received 30 November 2024 Accepted 22 January 2025 Published 14 February 2025 Volume 16 - 2025 Edited by Sally C

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The above-noted studies showed no detrimental impact of e-cigarette aerosol exposure on the cultures