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In addition, limited membrane permeability and susceptibility to enzymatic degradation hinder ginsenosides from accumulating in target tissues, often necessitating higher or more frequent dosing

Incorporating these agents into lipid-based nano-systems such as liposomes, ethosomes, nanogels, or nano-emulsions has emerged as an effective strategy to overcome these drawbacks [124, 125]

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Jensen et al., 2015)

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