labial melanotic macule pathology outlines

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Name: labial melanotic macule pathology outlines melanotic macule on face Oral
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Furthermore, it promotes the polarization of microglia from the pro-inflammatory M1 phenotype (indicated by a decrease in the CD86 + ratio) to the anti-inflammatory M2 phenotype (indicated by an increase in the CD206 + ratio)

This state, characterized by an imbalance between ROS production and elimination by the antioxidant system in favor of ROS formation, is termed oxidative stress (Sies 2023)