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Agents with endothelial cell-modifying effects, for example, phosphodiesterase inhibitors (PDEi) (124) potentially have therapeutic effect in SPG patients with severe COVID-19

Similarly, the LEADER trial with liraglutide showed a numerically higher, though non-significant, rate of diabetic retinopathy events compared to placebo (HR, 1.15

The nature and treatment of the cancer are the main factors influencing the short-term development of fat accumulation after anticancer therapy [58]

Arsenic binding induces a conformational change in the structure of the protein (PML-RARa), facilitating its oligomerization

In the second part of the review, the current evidence of the role of impaired barrier function in the pathophysiology of selected gastrointestinal and liver diseases is discussed