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Deficiency in vitamin B complex may result in digestive problems, including indigestion, reduced appetite, and unintentional weight loss

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In addition, the extracellular matrix elaborated by perivascular cells such as pericytes (retina) and mesangial cells (glomerulus) is increased, brought about by changes in synthesis and turnover of its component proteins and glycosaminoglycans

In this pathway, methylcobalamin provides the methyl group that couples to carbon monoxide (derived from CO 2 ) to afford acetyl-CoA

The focus of this article is water-soluble vitamins like vitamin C and vitamin B 12

doi: 10.3389/FONC.2017.00085 237 MarksJR