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Description

If the mice could not find the platform within 60 s, the time spent finding the platform was recorded as 60 s

There is no regulator-approved time-course expectation

J Am Soc Nephrol (2016) 27(8):22705

Why did the FDA restrict BPC-157

In the HD model, reduced expression and deacetylase activity of SIRT3, which in turn prevents the deacetylation of LKB1 and SOD2, leading to a decrease in the level of NAD + , defects in mitochondrial biogenesis and accumulation of ROS