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10.3 Mechanistic conflicts and translational challenges in metabolic interventions Although ketogenic diets show promise in animal models, clinical outcomes are inconsistent

The rate of total surgical arthroplasty (TSA) at two and five years was compared between patients who underwent physical therapy (PT) within a year of being diagnosed with glenohumeral OA and patients who did not receive PT

3.2 TCA cycle dysregulation and accumulation of metabolic intermediates Dysregulation of key enzymes in the TCA cycle leads to abnormal accumulation of metabolic intermediates, further disrupting insulin signaling ( + , is facilitated by the high membrane potential (m) and succinate-driven reduction through complex II

A total of 49 (83%) wife-caregivers reported having experienced an MSD for a minimum of 6 weeks at the evaluation

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