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One hundred and twenty rats were randomly divided into five groups: (1) Sham group, 24 rats experienced the same surgical procedures as rats in the control group without collagenase VII injection

Dysregulated Type I interferon and inflammatory monocyte-macrophage responses cause lethal pneumonia in SARS-CoV-infected mice

Mitchell, N

This can be accomplished by any of numerous methods known in the art, e.g., by constructing them as part of an appropriate nucleic acid expression vector and administering it so that they become intracellular, e.g., by infection using defective or attenuated retrovirals or other viral vectors (see U.S

These exposures act via a mechanism involving hormonal dysregulation, oxidative stress buildup, DNA damage, and epigenetic alterations

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