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The data generated during this phase help define the dose range that may be explored in subsequent studies and contribute to understanding exposure-response relationships, pharmacokinetic behavior and safety considerations associated with the investigational compound

they see it as a data point

Santa Fe, NM: Sherman Asher, 2011

Those with HHs were older, more obese, and more likely female compared to those without HHs

TurnerJSO'HalloranJAKalaidinaEKimWSchmitzAJZhouJQet al

Recent advancements in nanodelivery systems, such as microneedle-assisted nanostructured lipid carriers, have enhanced localized drug delivery, showing significant inhibition of MDA-MB-231 cell migration and tumor growth in xenograft models [30]